Bo Su
Professor
· Work Address: College of Pharmacy, Nankai University
· Telephone:
· E-mail: subo@nankai.edu.cn
Research Areas
a) Development of new reactions occurring in a catalytic and selective manner by the design of transition metal-catalysts and ligands;
b) Synthesis of natural products and biologically active molecules, and exploration of their medicinal applications.
Awards
l National High-level Talents Programs (2020)
l Hundred Young Academic Leaders Program of Nankai University (2019)
l China Postdoctoral Science Foundation (2014)
l Excellent Doctoral Dissertation of Nankai University (2014)
l MSD (Merck, U.S.) Postdoc Scholar Fellowship (2013)
l Doctoral National Scholarship (China) (2012)
l Nankai-PPG (PPG Industries, Inc) Scholarship (2012)
l Nankai University Outstanding Student Award (2012)
l Wan Xiang Scholarship (2011)
l Tai Da Kai-Lai Ying Scholarship (2009)
l Nankai University Scholarship for Outstanding Student (2009)
l Outstanding Graduates Award of ZhengZhou University (2008)
5. Social Service
Early Career Advisory Board Member (2022-present)
Guest Editor for Molecules (2021)
Editorial Board as Topic Editors for Molecules (2020-present)
Research & Achievements
Peer-Reviewed Journal Papers: (*Corresponding author)
32. Su B*, Hartwig J*, Development of Chiral Ligands for the Transition Metal‐catalyzed Enantioselective Silylation and Borylation of C‐H Bonds Angew. Chem. Int. Ed. 2022, 61, 9, e202113343
31. Liu J, Su B*, Chen M*，Cu-Catalyzed Highly Stereoselective Syntheses of (E)-δ-Vinyl-homoallylic Alcohols Org. Lett. 2021, 23, 6035-6040
30. Oeschger R,1 Su B,1 Yu I, Ehinger C, Romero E, He S, Hartwig J, Science 2020, 368, 736-741 (1Equal contribution)
29. B Su, A Bunescu, Y Qiu, SJ Zuend, M Ernst, JF Hartwig. J. Am. Chem. Soc. 2020, 142, 7912-7919.
28. Y Xi,1 B Su,1 X Qi, S Pedram, P Liu, JF Hartwig J. Am. Chem. Soc. 2020, 142, 18213-18222 (1Equal contribution)
27. Su, B.;1 Lee T.;1 Hartwig, J. F., Ir-Catalyzed Intramolecular Silylation of C-H Bonds of Aliphatic Amines.
J. Am. Chem. Soc. 2018, 140, 18032. (1Equal contribution)
26. Su, B.; Hartwig, J. F., Ir-Catalyzed, Silyl-Directed, peri-Borylation of C-H Bonds in Fused Polycyclic Arenes and Heteroarenes Angew. Chem. Int. Ed. 2018, 57, 10163-10167.
25. Su, B.; Hartwig, J. F., Ir-Catalyzed Enantioselective, Intramolecular Silylation of Methyl C–H Bonds.
J. Am. Chem. Soc. 2017, 139, 12137-12140.
24. Su, B.; Zhou, T.-G.; Xu, P.-L.; Shi, Z.-J.; Hartwig, J. F., Enantioselective Borylation of Aromatic C−H Bonds with Chiral Dinitrogen Ligands. Angew. Chem. Int. Ed. 2017, 56, 7205-7208.
23. Su, B.; Zhou, T.G.; Li, X.W.; Shao, X.R.; Xu, P.L.; Wu, W.L.; Hartwig, J. F.; Shi Z.-J., A Chiral Nitrogen
Ligand for Enantioselective, Iridium-Catalyzed Silylation of Aromatic C-H Bonds. Angew. Chem. Int. Ed. 2017, 56, 1092-1096.
22. Su, B.; Cai, C.; Deng, M.; Wang, Q.-M., Spatial Configuration and Three-Dimensional Conformation Directed Design, Synthesis, Antiviral Activity, and Structure–Activity Relationships of Phenanthroindolizidine Analogues. J. Agric. Food. Chem. 2016, 64, 2039-2045.
21. Su, B.; Cao, Z.-C.; Shi, Z.-J., Exploration of Earth-Abundant Transition Metals (Fe, Co, and Ni) as Catalysts in Unreactive Chemical Bond Activations. Acc. Chem. Res. 2015, 48, 886-896.
20. Su, B.; Wei, J.B.; Wu, W.L.; Shi, Z.-J., Diversity-Oriented Synthesis through Rh-Catalyzed Selective Transformations of a Novel Multirole Directing Group. ChemCatChem 2015, 7, 2986-2990.
19. Su, B.; Zhang, H.; Deng, M.; Wang, Q.-M., An enantioselective strategy for the total synthesis of (S)-tylophorine via catalytic asymmetric allylation and a one-pot DMAP-promoted isocyanate formation/Lewis acid catalyzed cyclization sequence. Org. Biomol. Chem. 2014, 12, 3616-3621.
18. Su, B.;1 Deng, M.;1 Wang, Q.-M., Sodium Nitrite-Catalyzed Aerobic Oxidative Csp2-Csp3 Coupling: Direct Construction of the 4-Aryldihydroisoquinolinone Moiety. Adv. Synth. & Catal. 2014, 356, 977-981. (1Equal contribution)
17. Su, B.;1 Cai, C. L.;1 Deng, M.; Liang, D. M.; Wang, L. Z.; Wang, Q.-M, Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives. Bioorg. Med. Chem. Lett. 2014, 24, 2881-2884. (1Equal contribution)
16. Su, B.;1 Chen, F.;1 Wang, L.; Wang, Q.-M., Design, Synthesis, Antiviral Activity, and Structure–Activity Relationships (SARs) of Two Types of Structurally Novel Phenanthroindo/quinolizidine Analogues. J. Agric. Food. Chem. 2014, 62, 1233-1239. (1Equal contribution)
15. Yang, M. Y.; Su, B.; Wang, Y.; Chen, K.; Jiang, X. Y.; Zhang, Y. F.; Zhang, X. S.; Chen, G. H.; Cheng, Y.; Cao, Z. C.; Guo, Q. Y.; Wang, L. S.; Shi, Z. -J., Silver-catalysed direct amination of unactivated C-H bonds of functionalized molecules. Nature Commun. 2014, 5. 4707-4712.
14. Su, B.;1 Deng, M.;1 Wang, Q.-M., Bioinspired Construction of a Spirocyclohexadienone Moiety via Sodium Nitrite Catalyzed Aerobic Intramolecular Oxidative Phenol Coupling. Org. Lett. 2013, 15, 1606–1609. (1Equal contribution)
13. Su, B.;1 Chen, F. Z.;1 Wang, Q.-M., A Novel Strategy for the Synthesis of Phenanthroindolizidine alkaloids via one-pot Intramolecular Schmidt/ Bischler-Napieralski/ Imine-reduction reaction. J. Org. Chem. 2013, 78, 2775–2779. (1Equal contribution)
12. Su, B.; Deng, M.; Wang, Q.-M., The first enantioselective approach to 13a-methyl-14-hydroxyphen- anthroindolizidine alkaloids: synthetic studies towards hypoestestatin 2. Eur. J. Org. Chem. 2013, 10, 1979–1985.
11. Su, B.; Cai, C. L.; Wang, Q.-M., Enantioselective Approach to 13a-Methylphenanthroindolizidine Alkaloids. J. Org. Chem. 2012, 77, 7981–7987.
10. Su, B.; Li, L.; Hu, Y. N.; Liu, Y. X.; Wang, Q.-M., A Novel Sodium Nitrite-Catalyzed Oxidative Coupling for Constructing Polymethoxyphenanthrene Rings. Adv. Synth. Catal. 2012, 354, 383–387.
9. L Li, B Su, Y Liu, Q Wang An Unprecedented Cyano-Induced Sodium Nitrite-Catalyzed C (sp3)-H and C (sp2)-H Coupling Reaction Current Organic Synthesis 2018, 15, 989-994.
8. H Zhang, G Li, B Su, M Deng, YX Liu, YC Gu, QM Wang Total synthesis of the reported structure of 13a-hydroxytylophorine Scientific reports 2017, 7, 1-7.
7. Deng, M.; Su, B.; Zhang, H.; Liu, Y. X.; Wang, Q.-M., Total synthesis of phenanthroindolizidine alkaloids via asymmetric deprotonation of N-Boc-pyrrolidine. Rsc Adv. 2014, 4, 14979-14984.
6. Chen, F.; Su, B.; Wang, Q.-M., Asymmetric synthesis of (S)-tylophorine and (S)-cryptopleurine via one-pot Curtius rearrangement and Friedel-Crafts reaction tandem sequence. Org. Chem. Front. 2014, 1, 674-677.
5. Wu, M.; Li, L.; Su, B.; Liu, Z. H.; Wang, Q., First total synthesis of (+)-6-O-desmethylantofine. Org. Biomol. Chem. 2011, 9, 141-145.
4. Wu, M.; Li, L.; Feng, A. Z.; Su, B.; Liang, D. M.; Liu, Y. X.; Wang, Q.-M.,“First total synthesis of Papilistatin.” Org. Biomol. Chem. 2011, 9, 2539-2542.
3. Wang, K. L.; Su, B.; Wang, Z. W.; Wu, M.; Li, Z.; Hu, Y. N.; Fan, Z. J.; Mi, N.; Wang, Q.-M., Synthesis and antiviral activities of phenanthroindolizidine alkaloids and their derivatives. J. Agric Food Chem. 2010, 58, 2703-2709.
2. Wang, K. L.; Hu, Y. N.; Wu, M.; Li, Z.; Liu, Z. H.; Su, B.; Yu, A.; Liu, Y.; Wang, Q.-M., “m-CPBA/TFA an efficient nonmetallic reagent for oxidative coupling of 1,2-diarylethylenes.” Tetrahedron. 2010, 66, 9135-9140.
1. Wang, K. L.; Hu, Y. N.; Li, Z.; Wu, M.; Liu, Z. H.; Su, B.; Yu, A.; Liu, Y.; Wang, Q.-M., A simple and efficient oxidative coupling of aromatic nuclei mediated by manganese dioxide. Synthesis. 2010, 7, 1083-1090.
Teaching
[1] Undergraduate: Advanced Organic Chemistry
[2] Graduate: Advanced Organic Chemistry
