Zhongbo Yu
Professor
· Work Address: College of Pharmacy, Nankai University
· E-mail: zyu@nankai.edu.cn
Research Areas
Single-molecule Biophysics, Telomere Biology, Epigenetics
Social Service
2021-Present, Deputy secretary general, Single-molecule Biological Subsociety, Biophysical Society of China
Research & Achievements
Peer-Reviewed Journal Papers: (*Corresponding author)
[5] Liang L, Ma K, Wang Z, Janissen R, Yu Z. Dynamics and Inhibition of MLL1 CXXC Domain on DNA Revealed by Single-Molecule Quantification. Biophys J. 2021 Aug 17;120(16):3283-3291.
[4] Liang L, Wang Z, Qu L, Huang W, Guo S, Guan X, Zhang W, Sun F, Yuan H, Zou H, Liu H, Yu Z. Single-molecule multiplexed profiling of protein-DNA complexes using Magnetic Tweezers. J Biol Chem. 2021 Jan 22:100327.
[3] Li X, Wang M, Zheng W, Huang W, Wang Z, Jin K, Liu L, Yu Z. Dynamics of TRF1 organizing a single human telomere. Nucleic Acids Res. 2020 Dec 21:gkaa1222.
[2] Ma X, Zhu M, Liu J, Li X, Qu L, Liang L, Huang W, Wang J, Li N, Chen JH, Zhang W, Yu Z. Interactions between PHD3-Bromo of MLL1 and H3K4me3 Revealed by Single-Molecule Magnetic Tweezers in a Parallel DNA Circuit. Bioconjug Chem. 2019 Dec 18;30(12):2998-3006.
[1] Li N, Wang J, Ma K, Liang L, Mi L, Huang W, Ma X, Wang Z, Zheng W, Xu L, Chen JH, Yu Z. The dynamics of forming a triplex in an artificial telomere inferred by DNA mechanics. Nucleic Acids Res. 2019 Sep 5;47(15):e86.
Teaching
Master and PhD: Nano medicinal chemistry
