LIU YIJIN
Professor
· Work Address: College of Pharmacy, Nankai University
· Telephone:
· E-mail: ribozyme_lab@foxmail.com
Research Areas
Nucleic acid structure; RNA catalysis; RNA drug design; DNA damage repair
Awards
[1] 2008, Cancer Research UK, China Fellow Program
[2] 2018, Young talent program from oversea, Tianjin
5. Social Service
[1]2017-2020, Member, British Biophysical Society
[2]2014-present, Member, RNA society
[3]2018-present, Member, Biophysical Society of China
Research & Achievements
Peer-Reviewed Journal Papers: (*Corresponding author)
1.Liu,Y., and and D. M. J. Lilley (2017). Crystal structures of cyanine fluorophores stacked onto the end of double-stranded RNA." Biophysical Journal 113(11):2336-2343
2.Liu, Y., T. J. Wilson and D. M. J. Lilley (2017). "The structure of a nucleolytic ribozyme that employs a catalytic metal ion." Nat Chem Biol 13(5): 508-513.
3.Wilson, T. J., Y. Liu, C. Domnick, S. Kath-Schorr and D. M. Lilley (2016). "The Novel Chemical Mechanism of the Twister Ribozyme." J Am Chem Soc 138(19): 6151-6162.
4.Liu, Y., A. D. Freeman, A. C. Declais, T. J. Wilson, A. Gartner and D. M. Lilley (2015). "Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA." Cell Rep 13(11): 2565-2575.
5.Lilley, D. M., Y. Liu and T. J. Wilson (2015). "84 The crystal structure and catalytic mechanism of the twister ribozyme." J Biomol Struct Dyn 33 Suppl 1: 54-55.
6.Liu, Y., T. J. Wilson, S. A. McPhee and D. M. Lilley (2014). "Crystal structure and mechanistic investigation of the twister ribozyme." Nat Chem Biol 10(9): 739-744.
7.Freeman, A. D., Y. Liu, A. C. Declais, A. Gartner and D. M. Lilley (2014). "GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes." J Mol Biol 426(24): 3946-3959.
Teaching
[1]Master: Structure-assisted drug design
[2]phD: Structural pharmacology
