Bin Wang
Professor
· Work Address: College of Pharmacy, Nankai University
· Telephone: +86-22-23506290
· E-mail: wangbin@nankai.edu.cn
Research Areas
Pharmaceutical Green Chemistry, Organic Chemistry Methodology
Research & Achievements
Peer-Reviewed Journal Papers: (*Corresponding author)
1. Zhao, G. H.; Li, B. Q.; Wang, S. S.; Liu, M.; Chen, Y.; Wang, B.*, PIFA-Mediated Dearomatizative Spirocyclization of Phenolic Biarylic Ketones via Oxidation and C-C Bond Cleavage. J. Org. Chem. 2020, 85 (14), 9367-9374.
2. Zhang, Y.-K.; Wang, B.*, Synthesis of α-Ketoamides from β-Ketonitriles and Primary Amines: A Catalyst-Free Oxidative Decyanation–Amidation Reaction. Eur. J. Org. Chem. 2019, 2019 (33), 5732-5735.
3. Wang, Z.; Zhang, L.; Zhang, F.; Wang, B.*, Synthesis of beta-Carbolines through Tetra-n-butylammonium Bromide-Mediated Cycloaromatization Reaction of N-Methylaniline with Tryptophan Derivatives. Chin. J. Org. Chem. 2019, 39 (8), 2323-2327.
4. Wang, Z.; Yu, Z.; Yao, Y.; Zhang, Y.; Xiao, X.; Wang, B.*, A practical synthesis of β-carbolines by tetra-n-butylammonium bromide (TBAB)-mediated cycloaromatization reaction of aldehydes with tryptophan derivatives. Chin. Chem. Lett. 2019, 30 (8), 1541-1544.
5. Yao, Y.; Wang, Z.; Wang, B.*, Tetra-n-butylammonium bromide (TBAB)-initiated carbonylation-peroxidation of styrene derivatives with aldehydes and hydroperoxides. Org. Chem. Front. 2018, 5 (16), 2501-2504.
6. Wang, B.*; Wong, H. N. C., Bromine-Mediated Cross-Dehydrogenative Coupling (CDC) Reactions. Bull. Chem. Soc. Jpn. 2018, 91 (4), 710-719.
7. Jiang, Y.-T.; Yu, Z.-Z.; Zhang, Y.-K.; Wang, B.*, N-Bromosuccinimide-Induced C–H Bond Functionalization: An Intramolecular Cycloaromatization of Electron Withdrawing Group Substituted 1-Biphenyl-2-ylethanone for the Synthesis of 10-Phenanthrenol. Org. Lett. 2018, 20 (13), 3728-3731.
8. Yang, Z. Y.; Tian, T.; Du, Y. F.; Li, S. Y.; Chu, C. C.; Chen, L. Y.; Li, D.; Liu, J. Y.; Wang, B.*, Direct intramolecular amination of tryptophan esters to prepare pyrrolo[2,3-b]indoles. Chem. Commun. 2017, 53 (57), 8050-8053.
9. Wang, H.; Wang, Z.; Wang, Y.-L.; Zhou, R.-R.; Wu, G.-C.; Yin, S.-Y.; Yan, X.; Wang, B.*, N-Bromosuccinimide (NBS)-Catalyzed C–H Bond Functionalization: An Annulation of Alkynes with Electron Withdrawing Group (EWG)-Substituted Acetyl Indoles for the Synthesis of Carbazoles. Org. Lett. 2017, 19 (22), 6140-6143.
10. Lu, T.; Jiang, Y.-T.; Ma, F.-P.; Tang, Z.-J.; Kuang, L.; Wang, Y.-X.; Wang, B.*, Bromide-Mediated C–H Bond Functionalization: Intermolecular Annulation of Phenylethanone Derivatives with Alkynes for the Synthesis of 1-Naphthols. Org. Lett. 2017, 19, 6344-6347.
11. Lou, M. M.; Wang, H.; Song, L.; Liu, H. Y.; Li, Z. Q.; Guo, X. S.; Zhang, F. G.; Wang, B.*, The Epoxidation of Carbonyl Compounds with a Benzyne-Triggered Sulfur Ylide. J. Org. Chem. 2016, 81 (14), 5915-21.
12. Xing, L. J.; Lu, T.; Fu, W. L.; Lou, M. M.; Chen, B.; Wang, Z. S.; Jin, Y.; Li, D.; Wang, B.*, 1,5-Diketones Synthesis via Three-Component Cascade Reaction. Adv. Synth. Catal. 2015, 357 (14-15), 3076-3080.
13. Li, H. Y.; Xing, L. J.; Lou, M. M.; Wang, H.; Liu, R. H.; Wang, B.*, Reaction of arynes with sulfoxides. Org. Lett. 2015, 17 (5), 1098-101.
14. Xu, T.; Zhou, W.; Wang, J.; Li, X.; Guo, J. W.; Wang, B.*, A mild method for the regioselective bromination of 2-aminopyridines. Tetrahedron Lett. 2014, 55 (36), 5058-5061.
15. Xing, L. J.; Wang, X. M.; Li, H. Y.; Zhou, W.; Kang, N.; Wang, P.; Wang, B.*, Metal-free synthesis of methylene-bridged bis-1,3-dicarbonyl compounds via oxidative C-C bond cleavage of tertiary aliphatic amines. RSC Adv. 2014, 4 (51), 26783-26786.
16. Gong, L.; Xing, L. J.; Xu, T.; Zhu, X. P.; Zhou, W.; Kang, N.; Wang, B.*, Metal-free oxidative olefination of primary amines with benzylic C-H bonds through direct deamination and C-H bond activation. Org. Biomol. Chem. 2014, 12 (34), 6557-60.
17. Li, H. Y.; Xing, L. J.; Xu, T.; Wang, P.; Liu, R. H.; Wang, B.*, An addition of benzylic sp3 C-H to electron-deficient olefins. Tetrahedron Lett. 2013, 54 (8), 858-860.
18. Li, L. T.; Zhou, L. F.; Li, Y. J.; Huang, J.; Liu, R. H.; Wang, B.*; Wang, P., Facile synthesis of 1,2,3-triazole analogs of SGLT2 inhibitors by 'click chemistry'. Bioorg. Med. Chem. Lett. 2012, 22 (1), 642-4.
19. Li, L. T.; Li, H. Y.; Xing, L. J.; Wen, L. J.; Wang, P.; Wang, B.*, Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines. Org. Biomol. Chem. 2012, 10 (48), 9519-22.
20. Li, L. T.; Huang, J.; Li, H. Y.; Wen, L. J.; Wang, P.; Wang, B.*, nBu4NI-catalyzed C3-formylation of indoles with N-methylaniline. Chem. Commun. 2012, 48 (42), 5187-9.
21. Huang, J.; Li, L. T.; Li, H. Y.; Husan, E.; Wang, P.; Wang, B.*, Bu4NI-catalyzed benzylic acyloxylation of alkylarenes with aromatic aldehydes. Chem. Commun. 2012, 48 (82), 10204-6.
Teaching
[1]Undergraduate: Organic Chemistry
[2]Master: Pharmaceutical Green Chemistry