Chen Yao
Professor
· Work Address: College of Pharmacy, Nankai University
· Telephone: +86-22-85358398
· E-mail: chenyao@nankai.edu.cn
Research Areas
1. Development of new biological agents, enzyme preparations and biomedical materials;
2. Develop new separation media with high performance based on biomolecules and new porous materials for efficient
separation and preparation of natural products and chiral drugs;
3.Understanding and analysis of biomolecular structure and functions to develop new drugs and formulation;
4.Developing new biomimetic and biocatalytic systems toward biomedicine, energy and other fields.
Awards
2014 National Self-funded International Student Award
Research & Achievements
Representative Peer-Reviewed Journal Papers: (*Corresponding author)
1. Mingmin Li, Shan Qiao, Yunlong Zheng, Yassin H Andaloussi, Xia Li, Zhenjie Zhang, Ang Li, Peng Cheng, Shengqian Ma, Yao Chen*, Fabricating Covalent Organic Framework Capsules with Commodious Microenvironment for Enzymes. J. Am. Chem. Soc. 2020, 142: 6675-6681.
2. Hongde An, Jie Song, Ting Wang, Nannan Xiao, Zhenjie Zhang, Peng Cheng, Shengqian Ma, He Huang, Yao Chen *, Metal-Organic Framework Disintegrants: Enzyme Preparation Platforms with Boosted Activity. Angew. Chem. Int. Ed. 2020, 59 (38), 16764-16769.
3. Huanrong Wang#, Lin Han#, Dong Zheng, Mingfang Yang, Yassin H. Andaloussi, Peng Cheng, Zhenjie Zhang, Shengqian Ma, Michael J. Zaworotko, Yifan Feng, Yao Chen*. Protein-Structure-Directed Metal-Organic Zeolite-like Networks as Biomacromolecule Carriers. Angew. Chem. Int. Ed. 2020, 59, 6263-6267.
4. Wen Duan#, Shan Qiao#, Mingjing Zhuo, Jiaxing Sun, Menglei Guo, Fei. Xu, Jinjin Liu, Ting Wang, Xiuxiu Guo, Yan Zhang, Jia Gao, Yueyun Huang, Zhenjie Zhang, Peng Cheng, Shengqian Ma*, Yao Chen*, Multifunctional Platforms: Metal-Organic Frameworks for Cutaneous and Cosmetic Treatment. Chem, 2021, 7, 450-462.
5. Yifan Feng, Huanrong Wang, Sainan Zhang, Yu Zhao, Jia Gao, Yunyi Zheng, Peng Zhao, Zhenjie Zhang, Michael J. Zaworotko, Peng, Cheng, Shengqian Ma*, Yao Chen*. Antibodies@MOFs: An In Vitro Protective Coating for Preparation and Storage of Biopharmaceuticals. Adv. Mater., 2019, 1805148 （封面文章）
6. Yao Chen, Vasiliki Lykourinou, Carissa Vetromile, Tran Hoang, Li-June Ming, Randy W. Larsen, Shengqian Ma*, How can proteins enter the interior of a MOF? Investigation of cytochrome c translocation into a MOF consisting of mesoporous cages with microporous windows. J. Am. Chem. Soc., 2012, 134, 13188-13191.
7. Zhengfeng Zhao, Yunlong Zheng, Chun Wang, Sainan Zhang, Jie Song, Yafei Li, Shengqian Ma, Peng Cheng, Zhenjie Zhang*, Yao Chen*, Fabrication of Robust Covalent Organic Frameworks for Enhanced Visible-Light-Driven H2 Evolution, ACS Catal., 2021, 11, 2098–2107.
8. Jinjin Liu, Wenjie Duan, Jie Song, Xiuxiu Guo, Zhifang Wang, Xinlei Shi, Jiajie Liang, Juan Wang, Peng Cheng, Yao Chen*, Michael J. Zaworotko*, Zhenjie Zhang*. Self-Healing Hyper-Cross-Linked Metal–Organic Polyhedra (HCMOPs) Membranes with Antimicrobial Activity and Highly Selective Separation Properties. J. Am. Chem. Soc. 2019, 141, 12064-12070.
9. Zhifang Wang#, Sainan Zhang#, Yao Chen*, Zhenjie Zhang*, Shengqian Ma*, Covalent Organic frameworks for separation applications. Chem. Soc. Rev. 2020, 9, 708-735
10. Jie Dong,# Hong-De An,# Ze-Kun Yue,# Sheng-Li Hou,# Yao Chen,* Zhen-Jie Zhang, Peng Cheng, Qian Peng,* and Bin Zhao*, Dual-Selective Catalysis in Dephosphorylation Tuned by Hf6‑Containing Metal−Organic Frameworks Mimicking Phosphatase. ACS Cent. Sci. 2021, 7, 831-840.
11. Sainan Zhang, Yunlong Zheng, Hongde An, Briana. Aguila, Chengxiong Yang, Yueyue Dong, Wei Xie, Peng Cheng, Zhenjie Zhang*, Yao Chen*, Shengqian Ma*. Covalent Organic Frameworks with Chirality Enriched by Biomolecules for Efficient Chiral Separation. Angew. Chem. Int. Ed. 2018, 57, 16754–16759.
12. Zhifang Wang, Qi Yu, Yubo Huang, Hongde An, Yu Zhao, Yifan Feng, Xia Li, Xinlei Shi, Jiajie Liang, Fusheng Pan, Peng Cheng, Yao Chen*, Zhenjie Zhang*, Shengqian Ma*. PolyCOFs: A New Class of Freestanding Responsive Covalent Organic Framework Membranes with High Mechanical Performance. ACS Central Sci. 2019, 5, 1352-1359.
13. An, Hongde#; Li, Mingmin#; Gao, Jia; Zhang, Zhenjie; Ma, Shengqian; Chen, Yao*; Incorporation of biomolecules in Metal-Organic Frameworks for advanced applications, Coordination Chemistry Reviews, 2019, 384, 90-106.
14. Vasiliki Lykourinou§, Yao Chen§, Xi-Sen Wang, Le Meng, Tran Hoang, Li-June Ming*, R. L. Musselman and Shengqian Ma*, Immobilization of MP-11 into a mesoporous metal–organic framework, MP-11@ mesoMOF: a new platform for enzymatic catalysis. J. Am. Chem. Soc., 2011, 133, 10382-10385. (§共同一作)
15. Shan Qiao, Wenjie Duan, Jiangyue Yu, Yunlong Zheng, Dong Yan, Fazheng Jin, Sainan Zhang, Zhenjie Zhang, Haixin Chen, He Huang, and Yao Chen*, Fabrication of Biomolecule−Covalent-Organic-Framework Composites as Responsive Platforms for Smart Regulation of Fermentation Application, ACS Appl. Mater. Interfaces, 2021, 13, 32058-32066.
Teaching
[1]Undergraduate: Global outlook and personal development
[2] Undergraduate: Molecular materials
[3]Master/PhD: Fundamentals of Pharmacology
