Basic Information
Name: Xiaoyu Ai
Professional title: Associate Professor
Work Address: College of Pharmacy, Nankai University
E-mail: aixiaoyu@nankai.edu.cn
Research Areas
Pulmonary drug delivery system, anti-tumor drug delivery system, pharmaceutics
Awards
None
Social Service
[1] 2020, Member, Pharmaceutical Branch of Chinese National Health Association
[2] 2021, Member, Tianjin Pharmacological Association - Respiratory Society
Research Project
1. Study on the construction of tumor microenvironment response composite nanocapsule and its deep penetration in tumor. National Natural Science Foundation of China (Youth Fund).
Research & Achievements
[1] Phenytoin silver: a new nanocompound for promoting dermal wound healing via comprehensive. Ai X, Liu H, Lu C, et al. Theranostics, 2017, 7(2):425-435.
[2] USP5 promotes epithelial–mesenchymal transition by stabilizing SLUG in hepatocellular carcinoma. Meng J, Ai X, Lei YY, et al. Theranostics, 2019, 9(2): 573-587.
[3] Sesquiterpene binding Gly-Leu-Ser/Lys “co-adaptation pocket” to inhibit lung cancer cell epithelial-mesenchymal transition. Ai X, Zhang H, Gao SY, et al. Oncotarget, 2017, 8 (41): 70192-70203.
[4] Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3-NF-κB signaling. Ai X, Qin Y, Liu H, et al. Oncotarget, 2017, 8 (59)：100216-100226.
[5] Dihydroartemisinin attenuates autoimmune thyroiditis by inhibiting the CXCR3/PI3K/AKT/NF-κB signaling pathway. Liu H, Qin Y, Ai X, et al. Oncotarget, 2017, 8 (70):115028-115040.
[6] Preparation and antitumor study of Dextran 70000-selenium nanoparticles and Poloxamer 188-selenium nanoparticles. Zhenzhen Wang, Liyuan Ji, Yimeng Ren, Menghan Liu, Xiaoyu Ai*, Cheng Yang*. AAPS PharmSciTech. 2021.
[7] Comparison of preparation of doxycycline enteric-coated pellets by powder layering method and liquid phase layering method. WANG Chun-ya, LI Ze-ping, LIU Zhi-qiang, Wang Shu-yan, Ai Xiao-yu*. Journal of Shenyang Pharmaceutical University.2021.
[8] Effect of Poloxamer 188 on dissolution, transport and stability of drug in solid dispersions. WEN Xia, WANG Zhen-zhen, LIU Zhi-qiang, Ai Xiao-yu*, YANG Cheng*. Journal of Shenyang Pharmaceutical University.2021.
[9] Research progress on targeted delivery of selenium nanoparticle and anti-cancer mechanism. WANG Zhen-zhen, Ai Xiao-yu*, YANG Cheng*. Journal of Shenyang Pharmaceutical University.2021.
[10] Star-shape redox-responsive PEG-sheddable copolymer of disulfide-linked polyethylene glycol-lysine-di-tocopherol succinate for tumor-triggering intracellular doxorubicin rapid release: head-to-head comparison. Ai X, Sun J, Zhong L, Wu C, Niu H, Xu T, Lian H, Han X, Ren G, Ding W, Wang J, Pu X, He Z.Macromol Biosci. 2014 Oct;14(10).
[11] Thin-film hydration preparation method and stability test of DOX-loaded disulfide-linked polyethylene glycol 5000-lysine-di-tocopherol succinate nanomicelles . Ai X, Zhong L, Niu H, He Z. AJPS, 2014, 9 (5): 244-250.
Teaching
[1] Undergraduate: Biopharmaceutics and Pharmacokinetics
[2] Undergraduate: Microbiology
