Jiansong Cheng

Publisher:Dates:2021-11-29Views:


     Associate Professor

· Work Address:  College of Pharmacy, Nankai University

· E-mail: jiansongcheng@nankai.edu.cn

Research Areas

Glycobiology, Biochemistry and Engineering

Research & Achievements

Peer-Reviewed Journal Papers: (*Corresponding author)

[1] Zhang P, Liu P, Xu Y, Liang Y, Wang PG, Cheng J*. N-acetyltransferases from three different organisms displaying distinct selectivity toward hexosamines and N-terminal amine of peptides. Carbohydr Res. 2019;472:72-75. (IF=2.07, 3).


[2] Hou Jingli#,Pan Yiwa#, Zhu Dashuai#, Fan Yueyuan, Feng Guowei, Wei Yongzhen, Wang He, Qin Kang, Zhao Tiechan, Yang Qiang, Zhu Yan, Che Yongzhe,Liu Yangping,Cheng Jiansong*, Kong Deling, Wang Peng George, Shen Jie* and Zhao Qiang*, Targeted delivery of nitric oxide via a 'bump-and-hole'-based enzyme-prodrug pair., Nature Chemical Biology, 2019, 15(2): 151~160. (IF=13.8)


[3] (2) Na Lu#; Jinfeng Ye#; Jiansong Cheng#; Aniruddha Sasmal; Chang-ChengLiu;Wenlong Yao; Jun Yan; Naazneen Khan; Wen Yi; Ajit Varki; Hongzhi Cao*,Redox-Controlled Site-Specific α2−6-Sialylation, J Am Chem Soc. 2019;141(11):4547-4552.


[4] Xu Yangyang, Fan Yueyuan, Ye Jinfeng, Wang Faxing, Nie Quandeng, Wang Li, Wang Peng George*, Cao Hongzhi*,Cheng Jiansong*, SuccessfullyEngineering a Bacterial Sialyltransferase for Regioselective alpha 2,6-sialylation, ACS Catalysis, 2018, 8(8): 7222~7227. (IF=11.41)


[5] Xu Yangyang#, Wu Zhigang#, Zhang Peiru, Zhu He, Zhu Hailiang, Song Qitao, Wang Li, Wang Faxing, Wang Peng George* andChengJiansong*, A novel enzymatic method for synthesis of glycopeptides carrying natural eukaryotic N-glycans, CHEMICAL COMMUNICATIONS, 2017, 53(65): 9075~9077. (IF=6.31)


[6] Song Qitao#,Wu Zhigang#, Fan Yueyuan, Song Woran, ZhangPeiru, Wang Li, Wang Faxing, Xu Yangyang, Wang Peng G*. and Cheng, Jiansong*, Production of homogeneous glycoprotein with multisite modifications by an engineered N-glycosyltransferase mutant, Journal of Biological Chemistry, 2017, 292(21): 8856~8863. (IF=4.012)


[7] Song Q, Zhang X, Li N, Shen J, Cheng J*. A propeptide-independent protease from Tannerella sp.6_1_58FAA_CT1 displays trypsin-like specificity. J Basic Microbiol. 2017; 57(1):50-56.(IF=1.584)


[8] Wu Z, Jiang K, Zhu H, Ma C, Yu Z, Li L, Guan W, Liu Y, Zhu H, Chen Y, Li S, Li J, Cheng J*, Zhang L*, Wang PG*. Site-Directed Glycosylation of Peptide/ Protein with Homogeneous O-Linked Eukaryotic N-Glycans. Bioconjug Chem.2016;27(9):1972-5. (IF=4.482)


[9] Wang, Y., Jiang, K., Ma, H., Zeng, W., Wang, PG., Yao, N., Han, W., Cheng, J.*, Wang, W.*, Enzymatic production of HMO mimics by the sialylation of galacto-oligosaccharides. Food Chem. 2015, 181, 51-6.


[10] Wang W, Ma T, Zhang B, Yao N, Li M, Cui L, Li G, Ma Z, Cheng J*. A novel mechanism of protein thermostability: a unique N-terminal domain confers heat resistance to Fe/Mn-SODs. Sci Rep. 2014; 4:7284.


[11] Wang L, Han W, Xie C, Hou J, Fang Q, Gu J, Wang PG, Cheng J*. Comparing the acceptor promiscuity of a Rosa hybrida glucosyltransferase RhGT1 and an engineered microbial glucosyltransferase OleD(PSA) toward a small flavonoid library. Carbohydr Res. 2013; 368:73-7.


[12] Han W, Cai L, Wu B, Li L, Xiao Z, Cheng J*, Wang PG. The wciN gene encodes an α-1,3-galactosyltransferase involved in the biosynthesis of the capsule repeating unit of Streptococcus pneumoniae serotype 6B. Biochemistry. 2012;51(29):5804-10.

Teaching

[1]Undergraduate: Biochemistry

[2]Master: Bioinformatics